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Job Postings
Nulabel Technologies
Scientist - Medicinal Chemistry, Integrated Drug Discovery

Location: Waltham, MA
To Apply: Click here ...

This is where ideas are pioneered and innovation takes shape. Where being a health journey partner takes shape — and where you can help bring ideas to life. Research & Development is the heart of our business. The clinical research, clinical development and clinical trials that are essential to new product development all happen here. Preclinical drug safety is rigorously tested and our program management teams ensure everything stays on track. Together, our R&D team ensures that our pipeline is protected and productive — and that the early stages of development run smoothly and effectively. Come be part of this journey.
 

Job Overview:
Accomplished synthetic organic and medicinal chemist with fundamental knowledge of medicinal chemistry principals and good track record of project impact as a key contributor.

Responsibilties:
  • Design and synthesize small molecule targets to drive programs to clinical candidate nomination.
  • Use reaction and reagent databases to select effective techniques/routes to maximize productivity and provide solutions to complex multi-step synthetic problems.
  • Prepare and characterize high purity target compounds and intermediates to meet aggressive project timelines.
  • Proficient in the use of analytical techniques for structural characterization and able to interpret simple to moderately complex NMR spectra.
  • Register compounds in corporate database and maintain notebooks according to SOP.
  • Champion new chemistry techniques, reagents and methodology in discovery chemistry and participate in group/lab responsibilities.
  • Fully understand SAR around the own work and the project and able to prioritize work based on emerging data.
  • Work independently and collaborate with other team members to design target compounds which address issues.
  • Interpret biological data (DMPK, pharmacology, safety) to identify issues and work independently to design target compounds to resolve issues.
  • Ability to learn from the literature and meetings to solve problems.
  • Understand and articulate the scientific rationale of the project to other scientists.
  • Determine the relevance of patent search results and assess the patentability of new targets.
  • Actively participate in medicinal chemistry discussions communicating own science in a clear and precise manner and raising issues which positively influence direction of lead series.
  • Communicate and interact with other staff members in a professional and courteous manner.
  • Operate in the lab in a safe and efficient manner according to HSE guidelines and adhere to all mandatory company compliance requirements.
  • Adapt to changes and challenges in a productive and professional manner.
  • Act as an ambassador for the department and attend appropriate meetings to increase knowledge and stay current with the journal and patent literature.
 
Requirements & Qualifications:
    • Bachelor’s Degree with minimum 6 years of relevant experience in a biopharmaceutical setting or Master’s Degree with minimum 3 years of experience in a biopharmaceutical setting.
    • Recognized as a technical expert with growing scientific and subject matter expertise and innovative contributions.
    • Emerging track record as a contributor providing quality science that forms the basis for publications, presentations and patents and involvement in professional society.

    Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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    At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.