Date: September 30th, 2026
Host: Jnana and GSK
Location: The Broad Institute, Cambridge MA
About the ConferenceThe science will focus cutting edge research in Chemical Biology from both academic and industry labs in the areas of machine learning applied to drug discovery, translational chemical biology, targeted protein degradation, chemical proteomics, novel target identification/validation, forward thinking synthetic strategies for chemical biology and chemical imaging.
The symposium will be followed by a reception with appetizers and refreshments for the symposium speakers and attendees. We anticipate that there will be approximately 240 attendees. Our target audience is a diverse mix of chemical biologists, including students and professionals from industry and academia.
2026 tickets will be available in two waves (labeled: day 1 and day 2 – just denoting the day they go on sale). Wednesday, August 12 at noon and Thursday, August 13 at 5 pm. You may join the waitlist after the day 1 tickets sell out, but you should try to purchase in the second wave. If tickets are sold out after the second wave, you will find the waitlist under Day 1.
8:15 – 9:00 am Registration and coffee
9:00 – 9:05 am Opening remarks
9:05 – 9:35 am Logan Combee, GSK
Employing DNA-encoded Libraries for Molecular Glue Discovery
9:35 – 10:15 am Katherine Donovan, DFCI/Broad Institute
Unveiling the hidden interactome of CRBN molecular glues
10:15 – 10:25 am Flash Talk
10:25 – 10:45 am Coffee Break
10:45 – 11:15 am Robert Everley, Frontier
Understanding in vivo target occupancy relationships: insights from target vulnerability and turnover
11:15 – 11:55 am Jacob Geri, Weill Cornell
Spatial protein interactomics and proteome-wide biophysics with high resolution proximity labeling
11:55 – 12:05 pm Flash Talk
12:10 pm – 1:00 pm Lunch
1:00 – 1:40 pm Xiao Wang, MIT/Broad
Deconstruct and reprogram the RNA lifecycle
1:40 – 2:10 pm Mary Matyskiela, Neomorph
Pushing the boundaries of molecular glue therapeutics from discovery to the clinic.
2:10 – 2:50 pm John Schneekloth, NCI/U Michigan
Structure and Screening Based Approaches to Reveal Serendipitous Pharmacology from RNA-binding Molecules
2:50 – 3:00 pm Flash Talk
3:00 – 3:20 pm Coffee break
3:20 – 4:00 pm Chris Parker, Scripps
Expanding the Chemical Tractability of the Human Proteome
4:00 – 4:35 pm Steve Canham, Novartis
Phenotypic profiling by cell painting leads to identification of novel translation inhibitors
4:35 – 4:40 pm Closing remarks
4:40 – 6:30 pm Poster session and reception
Machine Learning
Translational Chemical Biology
Targeted Protein Degradation
Target Identification
Chemical Imaging
Morning
8:15 – 9:00 am Registration and coffee
9:00 – 9:05 am Opening remarks
9:05 – 9:35 am Logan Combee, GSK
Employing DNA-encoded Libraries for Molecular Glue Discovery
9:35 – 10:15 am Katherine Donovan, DFCI/Broad Institute
Unveiling the hidden interactome of CRBN molecular glues
10:15 – 10:25 am Flash Talk
10:25 – 10:45 am Coffee Break
10:45 – 11:15 am Robert Everley, Frontier
Understanding in vivo target occupancy relationships: insights from target vulnerability and turnover
11:15 – 11:55 am Jacob Geri, Weill Cornell
Spatial protein interactomics and proteome-wide biophysics with high resolution proximity labeling
11:55 – 12:05 pm Flash Talk
Afternoon
12:10 pm – 1:00 pm Lunch
1:00 – 1:40 pm Xiao Wang, MIT/Broad
Deconstruct and reprogram the RNA lifecycle
1:40 – 2:10 pm Mary Matyskiela, Neomorph
Pushing the boundaries of molecular glue therapeutics from discovery to the clinic.
2:10 – 2:50 pm John Schneekloth, NCI/U Michigan
Structure and Screening Based Approaches to Reveal Serendipitous Pharmacology from RNA-binding Molecules
2:50 – 3:00 pm Flash Talk
3:00 – 3:20 pm Coffee break
3:20 – 4:00 pm Chris Parker, Scripps
Expanding the Chemical Tractability of the Human Proteome
4:00 – 4:35 pm Steve Canham, Novartis
Phenotypic profiling by cell painting leads to identification of novel translation inhibitors
4:35 – 4:40 pm Closing remarks
4:40 – 6:30 pm Poster session and reception
Other Information
Parking information
The Broad is located in the heart of Kendall Square and is walking distance from the Kendall Square T-stop of the Red Line. There are also numerous parking garages in the area.
For driving directions from where you will begin your trip, enter “415 Main St, Cambridge, MA 02142”
Lactation rooms are available but require reservation. Please reach out to Erin Hickey at: hickeyer@broadinstitute.org
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