Chemical Biology in the HUB
Sept 14th, 2023
The Broad Institute 415 Main St Cambridge, MA 02142
LINK for registration via Eventbrite.
Chemical Biology in The HUB Symposium
This fifth-in-a-series of scientific talks will focus on cutting edge research in Chemical Biology from both academic and industry labs in the areas of translational chemical biology, machine learning, novel target identification and validation, chemical imaging, as well as new chemical modalities.
This day-long symposium will be followed by a reception with appetizers and refreshments for the symposium speakers and attendees.
We wish to thank all of the sponsors and volunteers from industry who are making this possible. Our sponsors include, in alphabetical order, The American Chemical Society, ACS Chemical Biology, ACS Central Science, Arrakis Therapeutics, AstraZeneca, Biogen, BMS, C4 Therapeutics, FogPharma, GSK, Jnana Therapeutics, Kymera, Merck, Northeastern Section of the ACS, Novartis, Pfizer, Sanofi, Vertex. Our organizers are pleased to continue this fall tradition this year and in the coming years; please be in contact with us (below) if you are interested in participating in future symposia through volunteering, through sponsorship, or other means.
Registration is required and a ticket will be necessary for admission to the symposium and the networking reception
Schedule of Events
8:15 – 9:00 am Registration and coffee
9:00 – 9:10 am Opening remarks
9:10 – 9:45 am Ed Chouchani, Harvard University
Systematic discovery of druggable redox switches on immunological proteins
9:45 – 10:20 am Danette Daniels, Foghorn Therapeutics
Targeting Chromatin Regulatory Proteins with Therapeutic Degraders
10:20 – 10:45 am Coffee Break
10:45 – 11:20 am Keriann Backus, UCLA
Global rewiring of the proteome by cysteine-reactive electrophiles
11:20 – 11:55 am Ben Ruprecht, Covant Therapeutics
Leaving a permanent mark – Harnessing covalent chemoproteomics to target native proteoforms
11:55 am – 1:00 pm Lunch
1:00 – 1:35 pm Justin Kim, DFCI
Bioorthogonally activated reactive species for target identification
1:35 – 2:10 pm Heather Murrey, Scorpion Therapeutics
Advances in Covalent Ligand Discovery Enable Development of New Cancer Therapeutics
2:10 – 2:45 pm Justin Rettenmaier & Matt Labenski, Jnana Therapeutics
RAPID: photoaffinity-based high-throughput ligand discovery in cells
2:45 – 3:05 pm Coffee break
3:05 – 3:40 pm Jonathan Hurov, FogPharma
Development of Stapled Peptide HeliconsTM for Inhibition of β-Catenin:TCF Interaction
3:40 – 4:15 pm Michelle Arkin, UCSF
Structure, function, and manipulation of ‘hub’ proteins and their partners
4:15 – 4:20 pm Closing remarks
4:20 – 6:30 pm Poster session and reception
Questions? Please contact: Jeremy Baryza, email@example.com
THE PUBLIC IS INVITED – RESERVATIONS ARE REQUIRED
What are my transport/parking options getting to the event?
The Broad is located in the heart of Kendall Square and is walking distance from the Kendall Square T-stop of the Red Line. There are also numerous parking garages in the area.
Please contact the organizers regarding carpooling and other options.
For driving directions from where you will begin your trip, enter “415 Main St, Cambridge, MA 02142”
Is my registration/ticket transferrable?
Yes, please contact Jeremy Baryza before September 12, 2022.
Additionally there will be a poster session and ample time for discussion, networking, and catching up with colleagues and friends.
Please come join us for our 5th year!