September 2023 Medicinal Chemistry Meeting Symposium

&

The 1,022nd Meeting of the Northeastern Section of the American Chemical Society

“Targeted Delivery”

Organized by the Medicinal Chemistry Section

of the Northeastern Section, American Chemical Society

Sponsored By

Thursday – September 21^st, 2023

Takeda Cambridge

35 Lansdowne Street, Cambridge Massachusetts 02139

 

3:00 pm                        Welcome

• Raj Rajur, Medicinal Chemistry Program Chair, CreaGen, Woburn, MA

3:10 pm                        Introductory Remarks (Moderator)

• Paul Greenspan/Rob Goodnow, Takeda, Cambridge, MA

3:15 pm – 4:00 pm        Hong Myung Lee, Ph.D., Takeda, Cambridge, MA

• Title: “Identification of a novel linker enabling bioconjugation of a cyclic dinucleotide for the STING antibody-drug conjugate TAK-500

4:00 pm – 4:45 pm        Guoqiang Wang, Ph.D., Ranok Therapeutics, Cambridge, MA

• Title: “Application of a chaperone mediated protein degradation platform to KRAS therapeutics”

4:45 pm – 5:00 pm        Break

5:00 pm – 5:45 pm        Adrian Hobson, Ph.D., AbbVie, Worcester, MA

• Title: “The Role of Medicinal Chemistry in Optimizing Antibody Drug Conjugates”

5:45 pm – 6:30 pm        Corey Anderson, Ph.D., C4 Therapeutics, Cambridge, MA

• Title: “In vitro and in vivo characterization of orally bioavailable CNS penetrant BTK degraders for the treatment of Multiple Sclerosis”

7:00 pm – 8:30 pm        Dinner

 

NESACS BOARD MEETING

The Board Meeting will be held from 4:30-5:30 PM.

 –

PUBLIC IS INVITED

 

YOU MUST REGISTER IN ADVANCE TO ATTEND THE SYMPOSIUM:  THERE IS NO REGISTRATION FEE

TO ATTEND THE SYMPOSIUM, DINNER RESERVATIONS ARE REQUIRED. PUBLIC IS INVITED

• Dinner reservations should be made no later than 11:30 PM, Friday, September 15, 2023. Reservations are to be made using Eventbrite: https://www.eventbrite.com/e/2023-medicinal-chemistry-symposium-targeted-delivery-tickets-709754945147 Members, $30; Non-members, $35; Retirees, $20; Students, $10.
• If you wish to join us for this meeting and not eat dinner, please register by 11:30 PM, Friday, December 15, 2023 at https://www.eventbrite.com/e/2023-medicinal-chemistry-symposium-targeted-delivery-tickets-709754945147
  • Select “Seminar only”.

Directions and Parking information

Please use google map: 35 Lansdowne Street, Cambridge Massachusetts 02139.

MBTA closest stop is Central Square on the red line. Bus lines 1 and 2.

Parking is available at 10 Green St., directly across from the symposium entrance. Parking is free if validated at the entrance desk.

Attendees will need to enter via the back entrance to the building, which is located on Green St.

Registration or other questions? Please contact: Dr. Paul Greenspan by email at paul.greenspan@takeda.com or Raj rajur; rrajur@creageninc.com

MedChem Group members:

Mark Ashwell; Scott Edmondson; Brian. Aquila; Blaise Lippa; Andrew Scholte; Peter Fuller; Michelle Lamb; Saraj_Buhrlage; Yun Ding; Adrian Hobson; Paul Scola; Lauren Monovich