September 2025 Medicinal Chemistry Symposium
Symposium: “Breakthroughs in Oncology Drug Discovery”
This meeting will be hosted by Merck in Boston, MA.
Registration is required and ends at 11:30 PM on Friday, September 5th, 2025.
Thursday – September 11th, 2025
Merck
33 Avenue Louis Pasteur
Boston, MA 02115
1:00 pm Welcome & Introductory Remarks
Raj Rajur, Medicinal Chemistry Program Chair
CreaGen, Woburn, MA
AND
Erin DiMauro ED Discovery Chemistry, Merck
1:15 pm – 2:00 pm Veronika Ehmke
Novartis, Basel
Title: Targeting the SHOC2-RAS interaction in RAS-mutant cancers
2:00 pm – 2:45 pm Meredeth McGowan
MOMA, Cambridge
Title: The Discovery of MOMA-341, a Chemically Distinct, Potent and Selective Covalent Inhibitor of Werner Syndrome Helicase (WRN)
2:45 pm – 3:15 pm Break
3:15 pm – 4:00 pm Brian White
Parabilis, Cambridge
Title: Discovery of FOG-001, a Clinical Stage Helicon Inhibitor of the Beta-Catenin/TCF4 Interaction
4:00 pm – 4:45 pm Alex Pasternak
Merck, Boston
Title: IL4i1 Inhibitors from Target Validation Through to First-In-Human Studies in Cancer Patients
4:45 pm – 7:00 pm Networking Reception
NESACS Med Chem Organizing Committee: Mark Ashwell; Brian Aquila; Blaise Lippa; Andrew Scholte; Michelle Lamb; Silvana Leit; Melissa Grenier-Davies; Paul Scola; Lauren Monovich; Jason Beiger; Paul Greenspan; Raj Rajur; David Candito; Michelle Lamb; Paul Scola
PUBLIC IS INVITED
YOU MUST REGISTER IN ADVANCE TO ATTEND THE SYMPOSIUM – THERE ARE NO WALK-INS ALLOWED
If you will only attend the Symposium (1-4:45 pm), please select the free “Meeting only” ticket.
If you will attend the Symposium and Networking Reception or just the Networking Reception, please select a Networking Reception plus Meeting ticket.
• Reservations should be made no later than 11:30 PM, Friday, 5th September, 2025.
Directions and Parking information
Please use google map: Merck Research Labs, 33 Avenue Louis Pasteur, Boston, MA 02115
MBTA closest subway stop is Longwood and Longwood Medical Area (~8-10 min walk).
Parking information: There is no free parking. Local Paid parking is available 3 Blackfan St.-Center For Life Science Garage, 77 Avenue Louis Pasteur, NRB Garage
Registration or other questions? Please contact: David Candito by email at david.candito@merck.com or Raj Rajur; rrajur@creageninc.com.
